Welcome to Betty Lou’s Seafood and Grill
At Betty Lou’s Seafood and Grill, we celebrate the rich bounty of the ocean blended with a vibrant atmosphere. Nestled in the heart of San Francisco, we invite guests to indulge in exquisite seafood, flavorful steaks, and a delightful selection of cocktails. Known for our Oysters on the Half Shell and delectable crab dishes, each meal showcases fresh, quality ingredients that tell a story of coastal culinary traditions. Enjoy a casual dining experience complete with outdoor seating, perfect for gatherings or family nights. Join us for a memorable dining experience, where every bite reflects our passion for food and community.
- 318 Columbus Ave San Francisco, CA 94133 United States Hotline: (415) 757-0569
Welcome to Betty Lou’s Seafood and Grill
Nestled in the vibrant heart of San Francisco at 318 Columbus Ave, Betty Lou’s Seafood and Grill is your go-to destination for a remarkable seafood and steak dining experience. Combining a relaxed, casual atmosphere with a variety of delectable offerings, this establishment is perfectly suited for family gatherings, friendly outings, or a casual dinner date.
Menu Highlights
At Betty Lou’s, the rich aroma of grilled seafood mingles with the comforting scent of barbecued steaks. The menu is a delightful cacophony of flavors. Here are some standout dishes:
- Oysters on the Half Shell: Choose between the West Coast at $3.75 or the East Coast at $4.75, and prepare for a taste sensation that transports you to the shores they hail from.
- Fried Calamari Ala Ray: A popular starter, this dish intricately fried to a golden crunch, is perfect for sharing at $24.
- Cracked Crab: Served chilled for $26, this dish is the epitome of freshness and flavor.
- Cocktail Offerings: Indulge in a refreshing Bay Shrimp Cocktail for $19 or elevate your experience with our exclusive Oyster Shooters for $6.00, perfect for sipping with friends.
A Relaxed Atmosphere
Betty Lou’s Seafood and Grill boasts both indoor and outdoor seating, including heated and covered options for those breezy San Francisco nights. The venue encourages a casual dress code and offers moderate noise levels—ideal for lively conversations. Be it the weekend happy hour specials or the weeknight dinners where the joy of dining soars, each visit is filled with the shared joy of delicious food.
Accessibility and Convenience
This restaurant is designed to cater to all. With wheelchair accessibility, ample parking, and even options to pay with cryptocurrency or cash, Betty Lou's makes dining effortless. Families are welcome, and the gender-neutral restrooms ensure everyone feels comfortable.
Final Thoughts
In conclusion, if you find yourself in San Francisco, make Betty Lou’s Seafood and Grill a must-visit. Whether you're savoring a succulent piece of steak or relishing the briny goodness of freshly shucked oysters, each dish is a celebration of taste. Good for dancing, with a pool table and televisions, it’s more than just a meal; it's an experience. Don't forget to check out their military discounts and catering options for your next special gathering!
For reservations or delivery orders, give them a call at (415) 757-0569.

Everything was very good. Service was good. We had a window seat so we could people watch. Arrived after the peak time and the place was less crowded and more quiet. It is a small place. They take reservations but we just walked in off the ...

Omg wow one of the best freshest seafood dishes I have ever had. The sauce, amazing. The service, phenomenal. What a wonderful place completely recommend. Dont pass on the homemade tiramisu. Both our seafood plates were completely packed with a diversity of fresh seafood.

We ate at Betty Lous for lunch and had a great meal here. The service and the food were both excellent. The scalloped potatoes with the halibut special were amazing and I would highly recommend.

We come to Betty Lous every few months for the fresh seafood and great service. We got the last classic cioppino of the day and we were so glad! Plentiful and heartwarming comfort food. ...

I was pleasantly surprised by this relatively new seafood bistro near a vibrant intersection of Columbus and Grant. I was surprised how easy it was to get a reservation on the same Saturday. They serve up some really good fresh seafood, and ...

Can I just say... that SF really knows how to do oyster shooters? Theyre wonderful, and I wish I can have more of them everytime. Wonderful oyster shooters, clams were super fresh and tasty. The service was friendly and attentive with abit of flair. I just wish I have more stomach capacity to try the cioppino which looks excellent

absolutely delicious meal that hit all the spots. shared the cioppino and the seafood linguine in tomato cream sauce and they were both to die for. Ill be taking the memory of them both home with me to try and recreate... my friend even said it would be fun to do a fusion cioppino of the tomato cream sauce with all the seafood in it!

Called to make reservations, receptionist kind, waiter knows the menu n specials. The drinks were served on point, dinner delicious!